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There is an ongoing debate in Brazil about the impact of the new corona virus pandemic on Brazilian education. The institutional and political crisis that revolved around the existence of the virus in the first months of the pandemic provided a national atmosphere of conflict between the federal, state and municipal governments, which resulted in an asymmetric institutional behavior in the educational sector, across the country, regarding the dialectic between education and illness. The present research proposes to analyze the experience of implementing non-face-to-face teaching in a municipal school in Bahia in the first pandemic year (2020), from two axes: (1) the educational challenges provided by the new corona virus pandemic and (2) the specificities of the student body in the learning process in the first pandemic year. The survey results indicate that political disputes around the covid-19 pandemic had a negative impact on the educational sector, providing an institutional imbalance in the actions of the secretariat and school unit. As well as the student's educational experience, it was hampered due to the inequalities increase in the municipality and educational difficulties related to technology.
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COVID-19 pandemic has put health systems worldwide under pressure. Thus, establish a triage protocol to support the allocation of resources is important to deal with this public health crisis. In this paper, a structured methodology to support the triage of suspected or confirmed COVID-19 patients has been proposed, based on the utilitarian principle. A decision model has been proposed for evaluating three treatment alternatives: intensive care, hospital stay and home isolation. The model is developed according to multi-attribute utility theory and considers two criteria: the life of the patient and the overall cost to the health system. A screening protocol is proposed to support the use of the decision model, and a method is presented for calculating the probability of which of three treatment is the best one. The proposed methodology was implemented in an information and decision system. The originality of this study is using of the multi-attribute utility theory to support the triage of suspected COVID-19 and implement the decision model in an information and decision system.
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The need to sense and track in real time through sustainable and multifunctional labels is exacerbated by the COVID-19 pandemic, where the simultaneous measurement of body temperature and the fast tracking of people is required. One of the big challenges is to develop effective low-cost systems that can promote healthcare provision everywhere and for that, smarter and personalized Internet of things (IoT) devices are a pathway in large exploration, toward cost reduction and sustainability. Using the concept of color-multiplexed quick response (QR) codes, customized smart labels formed by two independent layers and smart location patterns provide simultaneous tracking and multiple synchronous temperature reading with maximum sensitivity values of 8.5% K-1 in the physiological temperature range, overwhelming the state-of-the-art optical sensor for healthcare services provided electronically via the internet (eHealth) and mobile sensors (mHealth).
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Objective: To analyze the economic-financial and operational performance of Health Plan Operators (HPO), before (3Q2018-4Q2019) and during the pandemic (1Q2020-2Q2021) under the theory of institutional isomorphism. Method: This is descriptive documentary research that uses statistical techniques to compare medians (Wilcoxon and Kruskal-Wallis) and correlation (Spearman) between performance and socioeconomic indicators, considering the five Health Plan Operators (HPO) with the largest number of beneficiaries. Results: A statistically significant reduction was observed, after the beginning of the pandemic, for the indicators of profitability, expenses, cost variation, and financial result. On the other hand, there was a growth in current liquidity and an increase in the mean receipt timeframe of payments (CRPM) and event payment (PMPE). The performance comparison shows that in the pandemic, profitability and PMPE were no longer significantly different. As for the association between the variables, the unemployment rate shows the highest number of relationships with the performance indices. Theoretical/methodological contributions: Highlights the performance of the five largest OPS, considering the Sars-Cov-2 pandemic period, considering that these companies can be directly affected by the potential increase in demand for health care by their beneficiaries. By the theoretical prism of institutional isomorphism, these companies are references for the sector.
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Background: COVID-19 is responsible for a worldwide pandemic, causing more than 18,000 deaths to date in Portugal. Data already exists regarding the increased risk of adverse events in patients with cardiovascular diseases, however the impact of SARS-CoV-2 infection in patients (P) with congenital heart disease (CHD) is still under investigation. Purpose(s): To study the impact of COVID-19 in a adult patients with CHD Methods: Adult patients seen at the CHD outpatient's clinic at a tertiary centre, who became infected with SARS-CoV-2 infection up to December 2021 were included. Assessment of patients' symptoms, need for hospitalization and admission in an intensive care unit was assessed based on medical records. Result(s): We identified seventy-nine patients (pts) with COVID-19 infection. Symptoms were present in 67 (84%). The median age was 44 (15) years, 52% were females. Eight P (10%) had complex cyanotic disease;seven Tetralogy of Fallot;five (6%) transposition of great arteries;eight (10%) right ventricle obstacle;two (3%) atrioventricular canal defect;sixteen (20%) atrial septal defect;nine (11%) ventricular septal defect;eight (10%) aortic coarctation;two (3%) had Eisenmenger syndrome. 49% of P had previous surgery or percutaneous procedure. 63% of P were at New York Heart Association (NYHA) class of I and 30% at NYHA II. Mild symptoms were reported by 56 P (71%). Ten adults (7,9%) experienced moderate symptoms (dyspnea and hypoxia) that led to hospitalization for oxygen therapy, none required mechanical ventilation. One death was reported in an 83-year-old patient with non-corrected interventricular communication and compromised biventricular function. There was a significant association between the gravity of CHD and hospitalizations (p=0.02). Conclusion(s): Our pts had mainly mild to moderate symptoms and did not appear to have a disproportionately negative outcome;the need for hospitalization was more frequent in patients with higher CHD gravity. These findings are in line with the emerging data regarding COVID-19 in CHD P, and may be in part explained by the patient's young age and functional status.
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HLA molecules play a key role in transplant medicine and disease pathogenesis, being a useful tool in predicting disease progression and identifying potential solid organ donors (SOD). The Coronavirus disease 2019 (SARS-CoV-2) pandemic had a huge worldwide impact, which strongly affected the activity of different transplant programs. So far, it has been shown that HLA type may be a crucial differentiator between individuals who have varying occurrence, morbidity, and mortality response to SARS-CoV-2. In this work, we investigated if differences in the frequency of SOD HLA alleles, were impacted during SARS-CoV-2 pandemic. We performed a retrospective file audit of all HLA-typings done in 2 subsets of SOD pre-pandemic period (ppp) (n = 379) and pandemic period (pp) (n = 351), collected in equivalent timeframes. We discuss data for the major HLA-A, HLA-B, HLA-C, and HLA-DRB1 allele groups at serological phenotyping level. Overall, there was a 7% SOD decrease in the pp. Considering both periods, the most common allele groups were HLA-A2, HLA-B35, HLA-Cw7, HLA-DR7 and HLA-DQ2. For the ppp group, the most common alleles were HLA-A2, HLA-B35, HLA-Cw7, HLADR13 and HLA-DQ2, while in the pp group the most common alleles were HLA-A2, HLA-B44, HLA-Cw7, HLA-DR4 and HLA-DQ2. When comparing both populations at the serological phenotyping level an increased in relative frequency was found for 10, 12, 8, 8 and 2, and a decreased was found for 10, 24, 8, 6 and 5 for HLA-A, -B, -C, -DR and -DQ, respectively. The significant variation within the HLA frequencies between the different pre-pandemic and pandemic groups highlights the value of population-specific HLA-typing. Furthermore, the identification of different frequencies among both populations will impact in patients HLA compatibility with SOD thus impacting their transplantability.
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During the COVID-19 pandemic, different groups had different perceptions of how dangerous the coronavirus was. This difference in behavior was intensified by the large amount of misinformation shared across social media. This work presents an analysis aimed at understanding the extent to which people perceived risk at different levels, and at uncovering the relationship between these differences and the spread of misinformation. In particular, we focus on Brazil, because it is well-known that its Ministry of Health has sponsored campaigns that raised suspicious regarding the effectiveness of the vaccines. To achieve this goal, we gathered tweets written in Portuguese related to the COVID-19 and analyzed their psycholinguistic traits. Among those traits, we found 'Anxiety' to be a good proxy for risk perception. We validate this choice by showing that, at moments of high (resp. low) infection rates in the world, the Anxiety score was higher (resp. lower). We grouped users into 'low' and 'high' risk perception based on the users' anxiety score, and analyzed the relation of each group with the spread of misinformation. Our results show that Twitter users with a lower perceived risk were more inclined to share fake news and harmful information, while the group with a higher level of anxiety tends to share more scientifically-backed information. This is an important step towards helping minimize the spread of false and harmful health information around the internet. © 2022 IEEE.
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Considering the first wave of the pandemic scenario and the necessary operation of policies and strategies that promote the population's self-care to mitigate the spread of the COVID-19 virus, we see here the actions taken in the official digital media of the federal public administration in the period from March to October 2020. To this end, we used the method of content analysis on all material advertised by the Ministry of Health on the platforms Twitter, Youtube, Facebook, Instagram, Spotify, Soundcloud, and official websites;ministry of health, pandemic hotsite, and health blog. With the analysis, we verified the prevalence of contents that privilege the illustration of the ministry's achievements, the 1. Self-promotion of the management itself, with 27.57% of the total publications, 2. Self-care promotion 18.87%, 3. Official data with 18.55%, 4. Daily news with 18.03%, 5. Technical communication for specialized audiences with 9.25%, and 6. Structural technical operation with 7.73%. With 3428 posts and 428,073,246 interactions evaluated, we saw self-care promotion content (18.87%) being suppressed by 81.13% of other aspects addressed by official government communication. In this way, we found that the absence of proper official communicative support at a level equivalent to the health demands presented in the pandemic that was established, leaves gaps in essential guidelines for the population, and even misinformation, which may have compromised the rigorous confrontation of the dissemination of the virus. © 2023, Centro Nacional de Informacion de Ciencias Medicas. All rights reserved.
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COVID-19 let sequelae beyond the respiratory system, including in skeletal muscle and in immune response. We evaluated the effects of 12 weeks of pulmonary rehabilitation (PR), 3x/week, constituted by aerobic and resistance training on 28 moderate and severe post-COVID-19 patients. The results demonstrated that PR improved lung function, FVC (p<0.02), FEV1 (p<0.02), FEV1/FVC (p<0.01), MEF25% (p<0.006), MEF50% (p<0.03), and MEF75% (p<0.02). PR improved lung mechanics, respiratory impedance (Z5hz, p<0.03);respiratory reactance (X5Hz, p<0.01), resistance of the whole respiratory systems (R5Hz, p<0.03), central airway resistance (RCentral, p<0.03), and peripheral airway resistance (RPeripheral, p<0.02). PR improved peripheral muscle strength, increasing right (p<0.02) and left (p<0.01) hand grip strength and respiratory muscle strength, increasing maximum inspiratory (p<0.02) and expiratory (p<0.03) pressure. Of note, PR reduced pulmonary inflammation (breath condensate), reducing the levels of pro-inflammatory cytokine IL-1beta (p<0.0001) and IL-6 (p<0.0001), while increased the levels of anti-inflammatory cytokine IL-1RA (p<0.0004) and IL-10 (p<0.003), beyond to increase the levels of IFN-gamma (p<0.0002) and IFN-beta (p<0.008). PR reduced the serum levels of pro-inflammatory IL-1beta (p<0.006) and IL-6 (p<0.01), while increased the levels of anti-inflammatory cytokine IL-1RA (p<0.0001) and IL-10 (p<0.0001), increasing the levels of IFN-gamma (p<0.02) and IFN-beta (p<0.001). PR reveals to be beneficial for post-COVID-19 patients, mitigating the sequelae observed in the respiratory system, skeletal muscle and in the immune response.
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The COVID-19 pandemic continues to increase social, economic, and psychological risks, including increased perceived stress - or the degree to which a person perceives a stressor and their ability to cope with it. The current study uses novel data collected during the COVID-19 pandemic to assess the role of a range of demographic and disaster-related experiential variables on perceived stress (n = 744). Hierarchical linear regression indicates that women experience greater perceived stress than men and as age and educational attainment increase, perceived stress decreases. Respondents experiencing rent/mortgage stress, job loss due to the COVID-19 pandemic, anticipated reliance on others, and worry about ongoing impacts of COVID-19 on their physical health, the economy, and personal relationships also experience increased perceived stress. Results provide empirical evidence of risks stemming from the multiple concerns (i.e., financial, psychological, and physical health) of U.S. residents regarding the COVID-19 disaster. Findings indicate the need for policy and legislative actions, such as the U.S.-wide eviction moratorium, to support individuals suffering from multiple impacts from the pandemic and to reduce perceived stress and its attendant risks including increased incidents of posttraumatic stress and depression.
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Objective: To verify the presence of tomographic alterations in the paranasais sinus of patients diagnosed with Covid-19 and to evaluate the presence of an association between olfactory symptoms and the involvement of these sinus. Method(s): This is an observational cross-sectional study that analyzed computed tomography of the nose and paranasal sinus (SSCT) of patients with Covid-19 regarding the presence of mucous thickening in the paranasal sinus. Patients who underwent RT-PCR examination for detection of Covid-19 (SARS-CoV-2) and TCSPN infection from March 2020 to March 2021 were included. Patients with a history of previous nasosinusal surgery, recent facial trauma, age below 18 years or with incomplete information in medical records were excluded. Result(s): A total of 65 individuals were included, of whom 28 were diagnosed with Covid-19. In tomographic analysis, an association was observed between Covid-19 infection and mucous thickening of the bilateral maxillary sinus (p = 0.038) and mucous thickening of the bilateral ethmoidal sinus (p = 0.005). No significant association was found between mucous thickening of the sphenoid and frontal sinus with virus infection. The complaint of olfactory dysfunction was reported by 20% of the patients, with no association with tomographic alterations or Covid-19 infection. Conclusion(s): Covid-19 virus infection possibly causes an injury to the mucosa of ethmoidal cells due to the inflammatory process resulting from viral infection. The lesion of the mucosa of the ethmoidal sinuses may cause alteration in the drainage physiology of the maxillary sinuses due to blockade of the middle meatal tract - site of drainage of the maxillary sinus - and lead to edema of the mucosa of this sinus. This change in the mucosa of the ethmoidal sinus may also be the cause of olfactory disorders presented by patients, as well as may cause lesions in the olfactory nerve. Keywords: Covid-19;SARS-CoV-2;Anosmia;Tomography;Paranasal sinuses. Copyright © 2022
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Oliveira GT, Meireles A, Hudson TA, Soares ER, Souza HLR, Santos MP, Mauad FO, Nascimento BF, Marocolo M, Ferreira RM. Performance Expectation, Anxiety, and Motivation of Triathletes and Swimmers during Different Lockdowns Stages in Covid-19 Pandemic. JEPonline 2022;25(4):75-83. The purpose of this study was to analyze the levels of anxiety during the COVID-19 pandemic and the motivation to return to training and competitions according to sex, sports experience, and training status before and during the isolation of swimmers and triathletes. We used the structured questionnaires Sports Motivation Scale 2 and the Three-Factor Anxiety Inventory 2, and a semi-structured questionnaire containing questions related to age and sex, in addition to a set of general information about their sports practice, such as the level of experience, the number of training sessions per week, and the competitive level and training sessions before and during restriction. A significant difference was observed in the dimensions of anxiety in public autofocus and autonomic hyperactivity between sex during swimming, intrinsic motivation, and identified between modalities and perceived control between sex and between modalities. In general, there was no association between anxiety and motivation and sports level, modality, and sex of the athletes. © 2022,Journal of Exercise Physiology Online. All Rights Reserved.
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Objective: to analyze racial biases in the context of morbidity and mortality due to COVID-19 of Brazilian pregnant women from an intersectional perspective. Method: an ecological, documental study using epidemiological bulletins intended to monitor the novel coronavirus in Brazil. Data were collected in March and April 2021 and analyzed using descriptive statistics mediated by the intersectional theory-based methodology. Results: Afro-descendant pregnant women presented an average prevalence rate of 65.18% hospitalizations and 70.85% deaths due to COVID-19 in 2020. On the other hand, the average prevalence rate of hospitalizations and deaths among Caucasian pregnant women was 32.32% and 27.23%, respectively. Conclusion: A greater difficulty to access prenatal care, a high prevalence rate of comorbidities, poor working conditions and impossibility to leave work during the pandemic, institutional racism, and necropolitics adopted by the Brazilian government are potential explanations for the vulnerable context faced by this population © All Rights Reserved.
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The COVID-19 pandemic continues to increase social, economic, and psychological risks, including increased perceived stress - or the degree to which a person perceives a stressor and their ability to cope with it. The current study uses novel data collected during the COVID-19 pandemic to assess the role of a range of demographic and disaster-related experiential variables on perceived stress (n = 744). Hierarchical linear regression indicates that women experience greater perceived stress than men and as age and educational attainment increase, perceived stress decreases. Respondents experiencing rent/mortgage stress, job loss due to the COVID-19 pandemic, anticipated reliance on others, and worry about ongoing impacts of COVID-19 on their physical health, the economy, and personal relationships also experience increased perceived stress. Results provide empirical evidence of risks stemming from the multiple concerns (i.e., financial, psychological, and physical health) of U.S. residents regarding the COVID-19 disaster. Findings indicate the need for policy and legislative actions, such as the U.S.-wide eviction moratorium, to support individuals suffering from multiple impacts from the pandemic and to reduce perceived stress and its attendant risks including increased incidents of posttraumatic stress and depression.
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The immediate and new challenges of the current Covid-19 pandemic have made it hard for all of us;in this work in progress as an innovative practice, we look to both leverage the challenges and share our work so that others might see some benefit to these times and improve their courses. In particular, our focus is on creating automated tools to physically create exams and sample code for Digital Systems and Computer Architecture courses. Additionally, we focus on shifting, traditional in-person labs to online, personalized formats for Digital Systems and Embedded Systems so that both educator and learner can still provide/experience virtual computer engineering education. We focus on three courses (Digital System Design, Computer Architecture/Organization, and Embedded System Design) as they are fundamentally driven by the implementation and execution of "algorithms". From this starting point, we have created tools to generate sample code and exams, and have found means to virtualize labs and hands-on activities. In particular, we have created Python tools that allow educators to personalize code and problems, create these codes/problems (as text files or incorporated in word documents), and email these documents to students. This provides the means to create problems and code examples that are different from their peers and can be assessed on a per individual basis to alleviate some of the challenges with live and proctored exams. Additionally, we have found tools and methods for students to virtually perform the hands-on portion of these three subjects without the need for traditional lab equipment. This requires students to spend less than 100 USD worth of equipment and software. Our goal is to share these resources and our methodologies to help in this time of crisis. Additionally, these tools and methods have forced us to innovate our teaching, and we will, likely, use these tools and methods in the future. We share these tools in hope that the computer engineering education community will join this process to help us all improve our student's education.
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The SARS-CoV-2 pandemic has demonstrated the need for genomic epidemiology surveillance. To date, various methodologies have been applied, including metagenomic approaches and amplicon-based sequencing associated with high-throughput sequencing platforms. We adapted some details in amplicon-based sequencing using a SARS-CoV-2 community panel (Illumina AmpliSeq), with additional modifications for balanced and high-quality sequencing using the MiSeq platform. The modified protocol was used to detect circulating SARS-CoV-2 variants in Goiás state, Brazil. Initially, RNA samples were obtained from swab samples from 15 patients from the state of Goiás, Brazil, in November/2020 and February/2021 to validate protocol steps. The libraries were prepared following AmpliSeq for Illumina workflow with modifications;subsequently, we analyzed 305 positive samples collected from the state of Goiás from December 2020 to July 2021. For protocol improvement, we removed the need to treat samples with DNAse and demonstrated the importance of quantification by qPCR before and after library dilution. No fragmentation pattern was observed in the samples analyzed with Bioanalyzer. The libraries returned sequencing results that were used for genome assembly and variant detection. We were able to assemble SARS-CoV-2 genomes from 318 samples, which were used to identify 13 variants of coronavirus circulating in Goiás throughout those months. Variants of concern, such as Alpha (B.1.1.7), Gamma (P.1) and Delta (B.1.617.2) were detected;the latter was detected at first in Goiás in April 2021. The modifications in the workflow we developed were successfully applied to detect SARS-CoV-2 variants, resulting in high coverage genome assembly, and they can be used to increase the number of genome sequences and aid in epidemiological surveillance in Brazil.